The Determination of IL-6 rs1800795 Polymorphism Distribution in Turkish National Cross-Country Skiing Athletes Sub-groups Created Referring to the 1km CCSTAs

Objective: Interleukin-6 (IL-6) is an effective and functional protein with a cytokine structure. IL-6 in the immune system like pro/anti-inflammatory response, muscle tissue hypertrophy repair. Our study aimed to investigate rs1800795 polymorphism distribution Turkish National Cross-Country Skiing Athletes determine advantageous genotype for endurance performance. 
 Methods: 34 athletes within 3 groups; General (Group-1), Women (Group-2), Men (Group-3) were enrolled study. Also each groups divided into sub-groups according their “1-kilometer cross-country average skiing-times (1 km-CCSTAs)”. Blood samples used DNA isolation genotyping completed by real time- PCR. Results: The groups' 1 km-CCSTAs 188.7 ± 22.4, 212.3 17.8, 177.4 14.1 seconds, respectively. We detected genotypes as 17 GG (50%) GC Group-1; 5 (45%) 6 (55%) Group-2; 12 (52%) 11 (48%) Group- 3. no CC groups. Chi-square Fisher’s test was statistical analysis. Conclusion: An increased ratio faster of group compared slower sub-groups. But we obtained significant only Group-3 (p